What is AMH testing?

AMH (Anti-Müllerian hormone) is produced by healthy ovaries and reflects ovarian reserve. AMH values decline with age, and this decline accelerates after 37. By around 40, very few—if any—healthy eggs may remain.

Why is AMH testing done?

AMH is a highly sensitive and specific test for the quantity and quality of eggs. It is reliable and not cycle-day dependent (can be done on any day).

• A low AMH indicates a serious decline in ovarian reserve and suggests moving to definitive treatment like IVFpromptly.

• Very low/near-zero AMH indicates minimal follicles and points to IVF with donor eggs.

• AMH also helps set the gonadotropin dose for stimulation and estimate egg numbers at retrieval.

• Noting lab variation, ~3 ng/ml (?22 pmol/L) is considered satisfactory.

What causes low AMH?

• Advancing age

• Low AMH even in the twenties (auto-immune disorders, Hepatitis B, HIV, hereditary galactosemia, X-linked disorders; many cases idiopathic/unknown)

• Familial/genetic premature decline (some cases)

• Previous ovarian surgery (e.g., endometriotic cyst removal, aggressive ovarian drilling)

• Cancer therapy (radiotherapy/chemotherapy)

What are the symptoms of low AMH?

Often no symptoms; many discover it on testing. Sometimes there are irregular or shorter cycles; if very low, periods may stop.

Is FSH testing important? What does high FSH mean?

FSH is a more crude indicator. Low AMH + high FSH typically confirm poor reserve/ovarian failure. FSH is less used now because it must be done on Day 2–3 of the cycle, but it’s still relevant to diagnose hypogonadotropic hypogonadism.

Who should get an AMH blood test?

• Single women considering fertility preservation/egg freezing

• Married women with >1 year infertility (part of comprehensive testing)

• Any woman >35 wishing to conceive with her own eggs

• Before every IVF/ICSI cycle at Janini IVF (to determine optimal injection dose)

• Women after cancer treatment

• Endometriosis patients awaiting/after surgery

Why choose Janini IVF?

AMH is accurate, but not the sole decision-maker. Choosing options like donor eggs must consider the whole picture: age, ovarian ultrasound, prior stimulation response, and any IVF outcomes.
At Janini IVF (Delhi), Dr.Dalal has successfully treated many low-AMH patients using individualised ovarian stimulation protocols to help them conceive with their own eggs. The clinic’s Cryo-accumulation program (collecting embryos over multiple cycles) has excellent success rates for this group.

FAQ 

1) Can AMH be done any day of the cycle?
Yes. AMH is not cycle-dependent; results remain consistent regardless of test day.

2) What if my AMH is very low or near-zero?
This suggests very few follicles. IVF should be considered promptly; donor-egg IVF may be advised.

3) Does a low AMH mean IVF will fail?
No. Low AMH signals reduced reserve, not impossibility. At Janini IVF, individualised protocols and (where appropriate) cryo-accumulation support good outcomes.

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